Determination of formic acid residues in calcipotriol by capillary column
Determination of formic acid residues in calcipotriol by capillary column Details:

Name: Capillary chromatography column

Stationary phase: 6% cyanopropylphenyl/94% dimethyl polysiloxane
Polarity: weak polar to medium polar stationary phase
Equivalent to USP stationary phase G43

Model: OV-624

Specification: 30m*0.32mm*1.8um
Application: Determination of formic acid residue in calcipotriol by capillary gas chromatography

Tengzhou Haohan Chromatography Instrument Technology Service Co., Ltd. established a method for the determination of formic acid in calcipotriol. Methods Using a gas chromatograph, an OV-624 capillary chromatography column (6% cyanopropylbenzene polysiloxane-94% dimethyl polysiloxane), 0.32 mm × 30 m, liquid film thickness of 1.8 μm; column Keep the temperature at 40℃ for 5 minutes, and increase the temperature to 150℃ at the rate of 10℃.min-1; hold for 10 minutes. Headspace injection, headspace bottle equilibrium temperature: 70℃, equilibrium time: 30 min, injection volume is 1 ml. With nitrogen as the carrier gas, the flow rate is 3 ml.min-1; FID detector. Results The linear relationship of formic acid was good, the correlation coefficient was greater than 0.999; the average recovery was 100.1%; the detection limit was 1.19 mg.L-1. Conclusion The method is simple, sensitive, reproducible and accurate. It is suitable for the determination of formic acid residue in calcipotriol.

Capillary column measurement of formic acid residues in calcipotriol Test spectrum: